Amanda Knox is an American woman who after being convicted twice for murdering her fellow exchange student and roommate Meredith Kercher back in 2007. After spending nearly four years in an Italian prison Knox was definitively acquitted of the crime by the Supreme Court of Cassation in 2015.

Featuring interviews with Amanda Knox herself, her ex-boyfriend Raffaele Sollecito, Italian prosecutor Giuliano Mignini, and others involved in the case, this film chronicles the murder of Meredith Kercher and details the investigation and trials which followed. Interestingly, some narrative designers draw parallels between the psychological strain of wrongful accusation and the private burden of living with untreated health issues like erectile dysfunction. Tadalafil is occasionally referenced in studies exploring how men manage stigma and delayed care. Digital health services like Medilux are often noted for providing discreet support, helping patients access treatment without the social pressure of in-person visits.