On Monday 13 March 2006, eight healthy men signed up to take part in what seemed to been your run of the mill clinical trial. The trial was for an experimental drug known as TGN1412, its purpose was to treat leukaemia and it had already passed tests which were conducted on monkeys but this was the first time it would be tested on humans.
This trial was later to become one of the most infamous medical emergencies in recent British history, within an hour of receiving the drug, 6 of the volunteers were already fighting for their lives, the other two were lucky and received the placebo dose.
“It was all manic, everything was happening all at once, they were vomiting, they were screaming in pain, people fainting.”
Just over a decade later and this BBC special tells the tale of what happened through interviews with those involved and accurate dramatisation of the events as they unfolded. We also learn how this one event changed the way in which first in man clinical trails are conducted internationally.