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The role of nephrostomy tube drainage is to aid in healing of the nephrostomy tract valsartan causes erectile dysfunction viagra soft 50 mg purchase without prescription, promote hemostasis, prevent urinary extravasation, drain infection, and allow re-entry if necessary. Comparison of nephrostomy tube size, shape, and tubeless and totally tubeless procedures is presented in Chapter 12. Institutional antibiograms aid in the selection of a most appropriate perioperative antimicrobial regimen. Importantly, it has been reported that urinary calculi may harbor bacteria even though bacteriuria is only intermittently present. In addition, the fragmentation of stones, despite sterile urine, may release preformed bacterial endotoxins and viable bacteria that place the patient at risk for septic complications. Therefore patients who have radiographic or clinical features suggestive of struvite, or in whom infection is suspected, should receive broad-spectrum antibiotics before surgery to reduce the risk for sepsis. For patients with indwelling stents, too, a course of antibiotic prophylaxis, particularly for gram-positive organisms, may be beneficial before instrumentation. Typically, general anesthesia is preferred; however, local anesthesia may be an option when general anesthesia is contraindicated. A local anesthetic, such as lidocaine, can be delivered into the access tract by use of an 8. Their ultimate place in the spectrum of therapies is not yet well defined, but they appear to be associated with less bleeding and pain. Special Situations Calyceal Diverticula Treatment of calculi within a calyceal diverticulum can be difficult, and percutaneous removal has the reported highest treatment success rate of all endourologic minimally invasive treatment modalities (Krambeck and Lingeman, 2009). Direct puncture is often difficult because of the small size of the cavity and the frequent occurrence of calyceal diverticula in the upper pole of the kidney. After successful puncture is achieved, negotiation of a guidewire into the renal pelvis is often not possible. A similar situation can occur when a stone fills a calyx so completely that a guidewire cannot be passed through the infundibulum into the renal pelvis or in the rare case of infundibular stenosis. If the calculi are visible on fluoroscopy, it is often preferable to puncture directly onto the stone. Once the diverticulum is punctured with an access needle, a guidewire is coiled within the diverticulum. It is important to ensure that not only the floppy tip of the wire but also the solid core is coiled within the diverticulum so that sufficient stabilization is provided for proper placement of coaxial dilators. With two guidewires coiled within the diverticular lumen, dilation of the tract can be performed safely. If a balloon dilator is used, once the balloon is inflated, the working sheath should be passed over the balloon so that it rests as closely as possible to the diverticulum. In small diverticula, this results in the placement of the sheath outside the diverticulum. An 11-Fr alligator forceps is passed through the rigid nephroscope and used to follow the wire and gently spread renal parenchyma to allow entry into the calyceal diverticulum under direct vision. Careful inspection of the urothelium with the rigid nephroscope, and in cases of a large diverticulum, a flexible nephroscope as well, is performed in an effort to identify a flattened renal papilla, which suggests an obstructed calyx rather than a diverticulum. The neck of the diverticulum is often difficult to identify because it can be diminutive. Methylene blue injected through the ureteral catheter can facilitate visualization of the ostium. Once a guidewire is passed into the renal pelvis, the neck of the diverticulum can be balloon dilated or incised. Alternatively, if the ostium is not identified, fulguration of the urothelium may be accomplished by a resectoscope equipped with a roller-ball electrode. The unique location and orientation of the horseshoe kidney are due to the incomplete cephalad migration and malrotation of the kidney, a consequence of the entrapment of the isthmus under the inferior mesenteric artery. The working sheath is then advanced over the nephroscope and into the diverticulum (C). Ureteral obstruction that may result from these anomalies can give rise to hydronephrosis, urinary stasis, sepsis, and calculi formation. Therefore a puncture of the dorsal or dorsolateral aspect of the kidney will be well away from major renal vessels. The lower pole calyces lie within a coronal plane, angled medially, and are seldom suitable for direct puncture. Because most of the calyces of horseshoe kidneys point either dorsomedially or dorsolaterally, they are more favorably positioned for puncture than are normal renal units. Because of the malrotation of the kidney, the renal pelvis may be more anteriorly located, and the length of the nephrostomy tract often exceeds the length of the rigid nephroscope, necessitating the use of flexible nephroscopy or multiple accesses. Flexible nephroscopy also may be required to gain access to the lower medial calyces, where stones are often found. Computed tomography­guided percutaneous access of a renal transplant for subsequent percutaneous nephrolithotomy procedure. Transplantation and Pelvic Kidneys Urolithiasis is uncommon in patients who have undergone renal transplantation; factors that may predispose transplant recipients to form calculi include metabolic abnormalities, foreign bodies (nonabsorbable suture material, forgotten stents), recurrent infection, and papillary necrosis. In either case, the renal pelvis is located medially, requiring that the kidney be rotated 180 degrees on its axis. Thus the posterior calyces point anteriorly and, consequently, an anterior approach to the kidney is similar to a posterior approach to native kidneys. In the usual percutaneous approach to a transplanted kidney the patient is placed in the lithotomy position, which allows simultaneous cystoscopic access to the bladder.

Posteriorly impotence natural purchase 50 mg viagra soft with mastercard, Colles fascia sweeps beneath the transverse perineal muscles, fusing with the posterior aspect of the perineal membrane. The penile shaft is composed of three erectile bodies: the paired corpora cavernosa and the corpus spongiosum. The prostatic muscle continues into the membranous urethra as the external smooth muscle sphincter. The external rhabdosphincter is often referred to as the external sphincter, and in the area of the membranous urethra are the muscles of recruitment that are not true sphincters. The more areolar and superficial fascia, the dartos fascia, is related more to the skin and its vasculature. The blood supply to the skin of the genitalia is based on the perineal branch­ scrotal branch of the deep internal pudendal artery and the superficial external pudendal vessels, branches of the femoral arteries. The penis is drained by three systems: the superficial, intermediate, and deep venous systems. The cavernosal nerves are a combination of the parasympathetic and the visceral afferent fibers and constitute the autonomic nerves to the penis. A transverse line between the ischial tuberosities divides the perineum into an anterior triangle containing the external urogenital organs and a posterior anal triangle. They attach to the inner surfaces of the ischium and ischial tuberosities on each side and insert at the midline into Buck fascia, surrounding the crura at their junction below the arcuate ligament of the penis. The midline fusion of the ischiocavernosus muscles and bulbospongiosus muscles is in the midline of the perineum. They are attached to the perineal body posteriorly and to each other in the midline as they encompass the bulbospongiosus and crura of the corpora cavernosa at the base of the penis. These muscles are confluent with the ischiocavernosus muscles laterally and at their insertion into Buck fascia, covering the dorsal vessels and nerves at the base of the penis. The perineal body receives fibers from the anterior portion of the anal sphincter and is the central point of insertion of the superficial transverse perineal muscles that arise at the ischial tuberosities. The bulbospongiosus muscle (midline fusion of the ischiocavernosus muscle) is fixed to the perineal body by its most posterior fibers. The deep transverse perineal muscles and fibers from the anterior portions of the levator ani muscles attach to the deep aspect of the perineal body. It is contained within two layers of fascia and incompletely covers the outlet of the pelvis anterior to the deep layer of the perineal body. All tissue has extensibility, inherent tension, and the viscoelastic properties of stress relaxation and creep. These physical characteristics are important in predicting the behavior of transferred tissue. A flap is tissue that has been excised and transferred with the blood supply preserved or surgically re-established at the recipient site. The issue of desiccation and hypertrophic growth, in the case of the bladder epithelial graft, has limited its use in the distal urethra. For urethral reconstruction, skin islands based on the dartos fascia or tunica dartos have been effectively used. The dermal graft has been used for years to augment the tunica albuginea of the corpora cavernosa. Musculocutaneous perforators from the artery to a muscle vascularize the skin and overlying subcutaneous fat. They may be transferred as free flaps but are usually transferred locally, left attached to the vascular pedicle. Perforating blood vessels from rich plexuses on the superficial and deep aspects of the fascia connect to perforator vessels that communicate with the microvasculature of the overlying paddle. In genital reconstruction, these flaps are based on the dartos fascia of the penis or are free flaps from the forearm. In addition, some patients have had an episode of diarrhea that preceded the development of arthritis. However, the classic triad is not present in most cases, and patients present with only arthritis affecting the knees, ankles, and feet in an asymmetrical distribution. Urethral involvement is usually mild and self-limited and constitutes a minor portion of the disease. Referred to as circinate balanitis, this lesion is diagnostic of reactive arthritis and typically appears as a shallow, painless ulcer with gray borders. In rare cases, urethritis causes severe inflammation with necrosis of the mucosa, producing uncompromising stricture disease. We have been unsuccessful in excision and replacement of the urethra in these cases. This approach may decrease the rheumatic manifestations associated with reactive arthritis. Patients typically present with hematuria or a bloody urethral discharge and occasionally with obstructive symptoms. The lesions may be single or multiple, and the urethral meatus is a common location. Although the diagnosis is often made with cystoscopy, which readily visualizes the dilated blood vessels, the lesion often extends beyond the point at which it is seen with cystoscopy. Because all reported cases of urethral hemangioma have been benign, management depends on the size and location of the lesion. Asymptomatic lesions do not require treatment and should be observed because hemangiomas can regress spontaneously.

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Medical Management Chemo dissolution as a sole treatment for bladder stones is time consuming and not completely efficient erectile dysfunction za generic viagra soft 100 mg online. In the current era its role is limited to use in select cases as an adjunct treatment. The treatment of chemodissolution is particularly effective for encrustation over long-term catheters. This can be considered as the treatment modality as well as a prophylactic measure (Phillippou et al. Any endoscopic intervention in such a situation is fraught with jeopardizing the integrity of the prosthesis or sphincter device. It has also been considered to be a treatment option in stones in neobladders and medically high-risk patients (Bhatia et al. These two factors are noted in 45% to 79% of all patients diagnosed with vesical calculi. The theory that secondary bladder calculi are due to outlet obstruction has been challenged. Large bladder stone and cystolitholapaxy equipment used for fragmenting bladder stones. Bladder Calculi in Urinary Diversions and Augmented Bladder Calculi can occur in the upper and lower tracts after augmentation or diversion, and the incidence varies depending upon the type of surgery performed. The cause of urolithiasis is multifactorial in patients who have urinary diversions. The reasons for stone formation can be divided into persistent bacterial colonization leading to infection, metabolic abnormalities, and anatomic and structural factors (Hensle et al. The common metabolic abnormalities that result in usage of ileum or colon for diversions is hyperchloremic metabolic acidosis, which in turn may cause hypercalciuria because of a decrease in absorption of calcium (Assimos, 1996). Loss of ileum can lead to enteric hyperoxaluria and diarrhea, which in turn can lead to stone formation (Terai et al. Most of the stones in this subset of patients are mainly struvite calculi, which proves that recurrent and persistent urinary tract infections are one of the most important causative factors in these patients (Arif et al. The organisms responsible for persistence of infections in these patients are urease-producing bacteria such as Pseudomonas, Proteus, and Klebsiella (Hertzig et al. The mucus in these diversions may also facilitate bacterial growth by aiding in deposition of bacterial biofilm and thereby making the penetration of antibiotics difficult (Blyth et al. The use of stomach for diversion helps in reducing the incidence of bladder calculi, but the complications associated with its use, such as hematuria dysuria syndrome and need for long-term proton pump inhibitors, discourages the use of stomach (Kronner et al. Urinary stasis can occur as the result of stomal stenosis in a case of conduit or poor emptying in a case of continent diversion. It has been proven that the incidence of calculi has significantly decreased in this subset of patients by shifting from nonabsorbable to absorbable sutures (Arif et al. Surgeries for calculi in patients with urinary diversions require special considerations. Preoperative knowledge of the type of diversion used is important, and it may help in deciding the operative modality. The accurate knowledge of anatomy is important and aids in planning the puncture in percutaneous approach and avoiding bowel injury. In patients in whom the stone in the conduit is due to stomal stenosis, removal of stone alone will lead to recurrence because of persistence of anatomic obstruction. In stones in continent diversions, such as those in cutaneous continent pouches, percutaneous approaches is preferable, and any treatment option that may cause injury to the continence mechanism should be avoided. In case of small burden stones in a neobladder, transurethral procedures can be done with minimal injury to the sphincter. In percutaneous technique either the Amplatz sheath or laparoscopic trocars can be used (Franzoni et al. Postoperative management of these patients includes adequate drainage of either the stoma or the pouches with a suprapubic catheter or stomal catheter in case of a stoma or per urethral catheter in case of neobladder. The prevention strategies include complete removal of stone, treatment of infection, correction of anatomic abnormalities, and prevention of mucus. Bladder Calculi in Patients With Spinal Cord Injury the risk of bladder stone formation increases in patients with neurogenic bladder resulting from spinal cord injury and meningomyelocele. The incidence depends on multiple factors such as level of lesion, the severity of the injury, previous incidence of stones, persistence of infection, and method of urinary drainage (Chen et al. For adults with spinal cord injury, the risk of bladder stone formation peaks at 3 months after injury, and within 10 years 15% to 30% of patients have formed at least one stone (Chen et al. After spinal cord injury two phases are important for calculi formation: the acute phase, in which most patients are immobilized, and the second phase, which is later after recovery. The reason for calculi formation during the acute phase may be immobilization hypercalciuria, which may lead to formation of calcium stones (Naftchi et al. These stones can occur anywhere in the urinary tract, including the kidney and the bladder. In the recovery phase the main reason for calculi Chapter 95 formation is the persistence of infection, which can be caused by either inadequate emptying or the methods deployed in emptying the urine (Burr et al. Other causes for stone formation in spinal cord injury patients include the increase in alkalinity of urine coupled with hypocitraturia in spinal cord injury patients. Patients on clean intermittent catheterization were found to have decreased incidence of bladder stones when compared with those on indwelling catheter (Ord et al. Indwelling Foley catheters should be avoided because they are prone to encrustation and can contribute to the formation of nephrolithiasis.