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All equipment used for vaccine storage should be of an acceptable standard and regularly maintained purchase avalide australia blood pressure medication names starting with a. Procedures for vaccine administration should maintain the cold chain at all times thus offering maximum efficacy buy cheap avalide 162.5mg line arrhythmia hypokalemia. Staff involved All staff at the immunization centre should be aware of the importance of the safe storage of vaccines and the maintenance of the cold chain cheap 180 mg cardizem with visa. One person is designated to be the overall responsible person for this and in her/his absence the deputy is responsible. Module 2 Page 53 Appendix 1 (continued) Responsibilities of the vaccine coordinator 1. Vaccine delivery: • Ensure that the delivery has taken no more than 48 hours • Place the vaccines in the refrigerator immediately • Ensure the delivery contents are correct 2. Vaccine storage: • Ensure the vaccine storage refrigerator is used for storage of vaccines only • Ensure the refrigerator is maintained regularly • The refrigerator should ideally be a self defrosting model • The maximum/minimum thermometer should be placed in the centre of the middle shelf so that it can measure the core temperature • The thermometer should be read and recorded daily • The temperature should usually be maintained between 2–8° C. Vaccine stocks: • The refrigerator should be stocked so that air can easily circulate internally, care should be taken to prevent over stocking • Ensure that sufficient stock is available to meet the demand • Vaccines should not be stored in the refrigerator door Staff Training All staff should be aware of the importance of maintaining the cold chain. The vaccine coordinator should ensure that all staff have access to information on the safe and effective storage of vaccines. Diarrhoea is the most common and the resultant dehydration is responsible for serious morbidity and mortality. Increased knowledge and awareness will lead to: • greater awareness of prevention measures; • early recognition of clinical signs and symptoms; • prompt and effective intervention, treatment and nursing care, and • improved public health measures. Dehydration is the main cause • Failing to continue breastfeeding until at least of death from acute diarrhoea although other one year of age: prolonged breastfeeding reduces important causes are septic shock, peritonitis and the incidence or severity malnutrition. The patient with diarrhoea not only of certain types of eats less, but also has an inability to absorb nutrients diseases causing at a time when nutrients are more in demand as a diarrhoea, such as result of the infection. Diarrhoea is also an economic burden bottles: these easily on developing countries; working days are lost and become contaminated expensive hospitalization for treatment may be with faecal bacteria and Breastfeeding. When milk is added to an unclean bottle it Definition becomes contaminated and if it is not consumed Diarrhoea is a clinical syndrome in which there is immediately, further bacterial growth occurs. If food is kept for several hours at room Mode of transmission temperature, bacteria in it can multiply many Infectious diarrhoea is spread by the faecal-oral times. The most common sources are • Drinking water that is contaminated with faecal contaminated food and water, person-to-person bacteria: water may be contaminated at its source contact and direct contact with infected faeces. Enteropathogens survive in ice and untreated • Contamination in the home may occur when a swimming pools. Protozoan parasites can survive storage container is not covered, or when a as cysts even in water that seems adequately contaminated hand comes into contact with water chlorinated. It is often believed that infant • Failing to breastfeed exclusively for the first 6 faeces are harmless, whereas they may actually Page 58 Module 3 contain large numbers of infectious viruses or Important pathogens bacteria such as rotaviruses or enterotoxic E. Several of these pathogens are important causes of • Animal faeces can transmit enteric infections such acute diarrhoea in all developing countries: as salmonella to humans.

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Diseases

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  • Hypertensive hyperkalemia, familial
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Vitamin D deficiency in the vation or chronic ill health) purchase avalide pills in toronto blood pressure medication nightmares, radiological features of rick- adult skeleton results in osteomalacia purchase avalide 162.5 mg visa arteria rectalis media, the pathognomon- ets may not be evident at the growth plate purchase generic vermox canada. In rickets of ic radiographic feature of which is Looser’s zone, named prematurity, little abnormality may be present at the after E. However, the bones are osteopenic and [44] are translucent areas in the bone that are composed prone to fractures. They are typically bi- diographic features of rickets may only become apparent lateral and symmetrical. Radiographically, they appear at puberty, during the growth spurt, with the metaphyseal as radiolucent lines that are perpendicular to the bone abnormalities predominating at the knee. Looser’s zones can occur in any bone, but most typ- provement in biochemical parameters (2 weeks) and clin- ically are found in the medial aspect of the femoral neck, ical symptoms. With treatment, the zone of provisional the pubic rami, the lateral border of the scapula, and the calcification will mineralize. They may involve the first and second ribs, in rated by translucent osteoid from the shaft of the bone which traumatic fractures are uncommon, being usually and may be mistaken for a metaphyseal fracture of child associated with severe trauma. Reduced bone density and poor definition of for Looser’s zones are the metatarsals and metacarpals, epiphyses are helpful distinguishing features for rickets. They may not The section of abnormal bone following healing of rick- always be visible on radiographs; radionuclide bone ets may be visible for a period of time, and give some in- scans are more sensitive in identifying radiographic oc- dication as to the age of onset and duration of the period cult Looser’s zones [45]. Eventually, this zone will become indistin- Looser’s zones must be differentiated from insuffi- guishable from normal bone with remodeling over a pe- ciency fractures that can occur in osteoporotic bone, riod of 3 to 4 months. The zone of provisional calcifica- particularly in the pubic rami, sacrum, and calcaneus. There will be evidence of retarded growth and development in rickets, but in my experience this tends to be more marked when the vitamin D deficiency is associated with chronic diseases that reduce calorie in- take, general well-being, and activity (i. Evidence of secondary hyperparathyroidism, with increased osteoclastic resorption, is always evident histologically, although not always radiographically. Metaphyseal chondrodysplasias encompass a variety of inherited bone dysplasias in which there are metaphy- seal abnormalities ranging from mild (Schmit Type) to severe (Jansen) [42]. Osteomalacia: to differentiate these dysplasias from other rachitic disor- Looser’s zone in the ders that the radiographic abnormalities at the metaphy- medial aspect of the ses may simulate. The other typical features of Paget’s disease serve as distinguishing radiological Glucose, inorganic phosphate, and amino acids are ab- features. However, as in rickets, osteomalacic bone is cose, or amino acids alone, or in combination, with addi- soft and bends. This is evident radiographically by pro- tional defects in urine acidification and concentration. There may be bowing of the long bones of the X-linked hypophosphatemia), or later in life (e.

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